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Capillary Electrophoresis Of Nucleic Acids, Vol. Ii: Practical Applications Of Capillary Electrophoresis By Mitchelson
1,406.00 EGP

Capillary Electrophoresis Of Nucleic Acids, Vol. Ii: Practical Applications Of Capillary Electrophoresis By Mitchelson

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Category Type
Microbiology
ISBN
9780896037656
Author
Mitchelson
Publisher
Humana Press
Description:

The development of PCR, which enables extremely small amounts of DNA to be amplified, led to the rapid development of a multiplicity of a- lytical procedures to utilize this new resource for analysis of genetic variation and for the detection of disease causing mutations. The advent of capillary electrophoresis (CE), with its power to separate and analyze very small amounts of DNA, has also ...

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PRODUCT INFORMATION

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    Specifications

    Category Type
    Microbiology
    ISBN
    9780896037656
    Item EAN
    2724462792157
    People
    Author
    Mitchelson
    People
    Publisher
    Humana Press
    Category Type
    Microbiology
    ISBN
    9780896037656
    Item EAN
    2724462792157
    People
    Author
    Mitchelson
    People
    Publisher
    Humana Press
    Technical Information
    Binding
    Paperback
    Languages and countries
    Book Language
    English
    Read more
  •  

    Description:

    The development of PCR, which enables extremely small amounts of DNA to be amplified, led to the rapid development of a multiplicity of a- lytical procedures to utilize this new resource for analysis of genetic variation and for the detection of disease causing mutations. The advent of capillary

    The development of PCR, which enables extremely small amounts of DNA to be amplified, led to the rapid development of a multiplicity of a- lytical procedures to utilize this new resource for analysis of genetic variation and for the detection of disease causing mutations. The advent of capillary electrophoresis (CE), with its power to separate and analyze very small amounts of DNA, has also stimulated researchers to develop analytical procedures for the CE format. The advantages of CE in terms of speed and reproducibility of analysis are manifold. Further, the high sensitivity of detection, and the ab- ity to increase sample throughput with parallel analysis, has led to the creation of a full range of analysis of DNA molecules, from modified DNA-adducts and single-strand oligonucleotides through to PCR-amplified DNA fragments and whole chromosomes. Capillary Electrophoresis of Nucleic Acids focuses on such analytical protocols, which can be used for detection and analysis of mutations and modification, from precise DNA loci through to entire genomes of organisms.Important practical considerations for CE, such as the choice of separation media, electrophoresis conditions, and the influence of buffer additives and dyes on DNA mobility, are discussed in several key chapters and within particular applications.

    • Author:Mitchelson
    • Publisher:Humana Press
    • ISBN:9780896037656
 

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